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CAS No. 1029044-16-3 | PLX3397 (Pexidartinib)

CAS No. 1029044-16-3 | PLX3397 (Pexidartinib)

Name: PLX3397 (Pexidartinib) CAS No.1029044-16-3 MF:C20H15ClF3N5 MW:417.81 Purity:98% Package: 5mg,25mg,200mg,500mg,1g Worldwide Delivery

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Product introduction

Introduction and application of CAS No. 1029044-16-3 | PLX3397 (Pexidartinib)

Synonyms:5-((5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl);

3-Pyridinemethanamine,N-[5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-;

N-[5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine;

5-((5-chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine;

Specification:

ITEMS	SPECIFICATION
CAS	1029044-16-3
MF	C20H15ClF3N5
MW	417.81
Density	1.458±0.06 g/cm3
Acidity coefficient	12.81±0.40
Color	White
Solubility	Soluble in DMSO (up to at least 10 mg/ml)
Form	Solid
Storage condition	-20°C

Biological activity:

Pexidartinib (PLX3397) is an orally available multi-target CSF-1R, Kit (c-Kit), and FLT3 receptor tyrosine kinase inhibitor with IC50s of 20nM, 10nM and 160nM respectively. Pexidartinib (PLX3397) can induce apoptosis and necrosis and has anti-tumor activity.

Package and transportation :

Package: 5mg,25mg,200mg,500mg,1g